Medical Director of Hematopathology, Flow Cytometry, and Cytopathology at Children's Hospital Colorado
Recognition & Awards
Summit award for excellence in teaching and the education of pathologists, University of Colorado School of Medicine, Department of Pathology
(2017)
Summit award for excellence in teaching and the education of pathologists, University of Colorado School of Medicine, Department of Pathology
(2013)
Summit award for excellence in teaching and the education of pathologists,, University of Colorado School of Medicine, Department of Pathology
(2011)
Summit award for excellence in teaching and the education of pathologists, University of Colorado School of Medicine, Department of Pathology
(2009)
Teaching award from Foundation to CURE Childhood Cancer, Foundation to CURE Childhood Cancer
(2009)
Publications
Liu X, Zhao Y, Luedke C, Yang L, Lu CM, Jug R, Pan Z, Wang D, Lorsbach R, Shi Y, Knez V, Liang X, Wang E. Infantile Leukemia - What Factors Determine Its Distinct Biological Nature? Clinicopathological Study of 78 Cases. International J Lab Hematol. Int J Lab Hematol. 2021 Apr 13. doi: 10.1111/ijlh.13540. Online ahead of print (PMID: 33847065).
Thiago Alves da Costa, Jacob N Peterson, Julie Lang, Jeremy Shulman, Xiayuan Liang, Brian M. Freed, Susan A. Boackle, Pilar Lauzurica, Raul M. Torres, and Roberta Pelanda. Central human B cell tolerance manifests with a distinctive cell phenotype and is enforced via CXCR4 signaling in hu-mice. The Proceedings of the National Academy of Sciences. Proc Natl Acad Sci USA. 2021 Apr 20;118(16):e2021570118. doi:10.1073/pnas.2021570118 (PMID: 33850015).
Knez V, Bao L, Carstens B, and Liang X. Analysis of clinicopathological and cytogenetic differences between B-lymphoblastic lymphoma and B-lymphoblastic leukemia in patients of childhood. Leuk Lymphoma. 2020;61:2129-2135 (32427530).
Nunns GR, Vigneshwar N, Kelher MR, Stettler GR, Gera L, Reisz JA, D'Alessandro A, Ryon J, Hansen KC, Gamboni F, Moore EE, Peltz ED, Cohen MJ, Jones KL, Sauaia A, Liang X, Banerjee A, Ghasabyan A, Chandler JG, Rodawig S, Jones C, Eitel A, Hom P, Silliman CC. Succinate activation of SUCNR1 predisposes severely injured patients to neutrophil-mediated ARDS. Ann Surg. 2020 Nov 18. doi: 10.1097/SLA.0000000000004644.
Kaleigh Erin Lindholm, Liming Bao, Billie Carstens, Xiayuan Liang. Down Syndrome (DS) with B-Cell Acute Lymphoblastic Leukemia (B-ALL) versus Non-DS B-ALL in Children and Young Adults: Pathogenetic Differences. Poster Presentation. 109th Annual Meeting, United States and Canadian Academy of Pathology. Los Angeles, CA. March, 2020.
Lucas CG, Gilani A, Solomon DA, Liang X, Maher OM, Chamyan G, Kleinschmidt-Demasters BK, Perry A. ALK-positive histiocytosis with KIF5B-ALK fusion in the central nervous system. Acta Neuropathol. 2019 Aug;138(2):335-337. PubMed PMID: 31119374
Klein C, Kleinschmidt-DeMasters BK, Liang X, Stence N, Tuder RM, Moore BE. A Review of Neuropathological Features of Familial and Adult Hemophagocytic Lymphohistiocytosis. J Neuropathol Exp Neurol. 2019 Mar 1;78(3):197-208. PubMed PMID: 30726926
Sopfe J, Endres A, Campbell K, Hayes K, Trout AT, Liang X, Lorsbach R, O'Brien MM, Cost CR. Castleman disease in pediatrics: Insights on presentation, treatment, and outcomes from a two-site retrospective cohort study. Pediatr Blood Cancer. 2019 May;66(5):e27613. PubMed PMID: 30680887
Knez V, Liu X, Schowinsky J, Pan Z, Wang D, Lorsbach R, Lu C, Luedke C, Haag M, Carstens B, Swisshelm K, Yang LH, Jug R, Wang E, Liang X. Clinicopathologic and genetic spectrum of infantile B-lymphoblastic leukemia: a multi-institutional study. Leuk Lymphoma. 2019 Apr;60(4):1006-1013. PubMed PMID: 30188223
Wilberger AC, Liang X. Primary Nonanaplastic Peripheral Natural Killer/T-Cell Lymphoma in Pediatric Patients-An Unusual Distribution Pattern of Subtypes. Pediatr Dev Pathol. 2019 Mar-Apr;22(2):128-136. PubMed PMID: 30334665
Care Philosophy
I love children and have a life-long commitment to patient care in pediatrics. Hematopoietic neoplasm is number one malignant neoplasm in children. I would like to contribute as much as I can to improve diagnosis and management of pediatric hematopoietic disorders.
General Information
Medical Schools:
MD, Capital Medical University - Beijing
(1982)
Residency Programs:
University of Arkansas College of Medicine Program, Pathology (1998)
University of Maryland Program, Pathology (1996)
Fellowships:
St. Jude Children's Research Hospital, Hematology
(1999)