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Michelle Leppert, MD

Assistant Professor, Neurology


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Medical School
  • MD, Emory University School of Medicine (2011)
Graduate School
  • MBA, Emory University (2011)
Undergraduate School
  • BS, Duke University (NC) (2005)
Internship
  • University of Colorado (University Hospital) Program (2012)
Residency
  • University of Colorado (University Hospital) Program, Neurology (2015)
Fellowships
  • University of Colorado (University Hospital) Program, Vascular Neurology (2016)
Languages Mandarin
Department Neurology

Publications

  • Leppert MH, Poisson SN, Carroll JD, Thaler DE, Kim CH, Orjuela KD, Ho PM, Burke JF, Campbell JD. Cost-Effectiveness of Patent Foramen Ovale Closure Versus Medical Therapy for Secondary Stroke Prevention. Stroke. 2018 Jun;49(6):1443-1450. PubMed PMID: 29720435
  • Nguyen GH, Mohler A, Leppert M, Parra C, Zeng YP, Prok L, Schowinsky J, Magro CM, Pacheco T, Ney D. Index Case of Cutaneous Follicular Mycosis Fungoides With Central Nervous System Involvement and Review of Literature. Am J Dermatopathol. 2018 Mar;40(3):185-190. PubMed PMID: 29470304
  • Ludt C, Leppert M, Jones A, Song J, Kuwayama D, Pastula DM, Poisson S. Multiple Strokes Associated With Elongation of the Hyoid Bone. Neurohospitalist. 2018 Jan;8(1):35-37. PubMed PMID: 29276562
  • Nyberg EM, Case D, Nagae LM, Honce JM, Reyenga W, Seinfeld J, Poisson S, Leppert MH. The Addition of Endovascular Intervention for Dural Venous Sinus Thrombosis: Single-Center Experience and Review of Literature. J Stroke Cerebrovasc Dis. 2017 Oct;26(10):2240-2247. PubMed PMID: 28606660
  • Johnston SC, Easton JD, Farrant M, Barsan W, Conwit RA, Elm JJ, Kim AS, Lindblad AS, Palesch YY. Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA. N Engl J Med. 2018 Jul 19;379(3):215-225. PubMed PMID: 29766750
  • Leppert M, Poisson SN, Carroll JD. Atrial Septal Defects and Cardioembolic Strokes. Cardiol Clin. 2016 May;34(2):225-30. PubMed PMID: 27150170
  • Schowinsky J, Leppert M, Ney D, Kleinschmidt-DeMasters BK. Prominent Vascular and Perivascular Eosinophilic Infiltrates Heralding CNS Mycosis Fungoides. J Neuropathol Exp Neurol. 2015 Oct;74(10):948-51. PubMed PMID: 26352990
  • Randleman JB, White AJ Jr, Lynn MJ, Hu MH, Stulting RD. Incidence, outcomes, and risk factors for retreatment after wavefront-optimized ablations with PRK and LASIK. J Refract Surg. 2009 Mar;25(3):273-6. PubMed PMID: 19370822
  • Randleman JB, Perez-Straziota CE, Hu MH, White AJ, Loft ES, Stulting RD. Higher-order aberrations after wavefront-optimized photorefractive keratectomy and laser in situ keratomileusis. J Cataract Refract Surg. 2009 Feb;35(2):260-4. PubMed PMID: 19185240
  • Leppert MH, Campbell JD, Simpson JR, Burke JF. Cost-Effectiveness of Intra-Arterial Treatment as an Adjunct to Intravenous Tissue-Type Plasminogen Activator for Acute Ischemic Stroke. Stroke. 2015 Jul;46(7):1870-6. PubMed PMID: 26012639
  • Leppert MH, Poisson SN, Sillau SH, Campbell JD, Ho PM, Burke JF. Is Prevalence of Atherosclerotic Risk Factors Increasing Among Young Adults? It Depends on How You Ask. J Am Heart Assoc. 2019 Mar 19;8(6):e010883. PubMed PMID: 30857455
  • Pollard R, Leppert M, Rawson C, Boehnke M, Honce J, Nagae L, Poisson S, Nyberg E. A Clinical Paradigm for Classifying Neurologic Symptoms to Screen for Emergent Large Vessel Occlusions. J Stroke Cerebrovasc Dis. 2019 Apr;28(4):929-934. PubMed PMID: 30638942
  • Leppert MH, Sillau S, Lindrooth RC, Poisson SN, Campbell JD, Simpson JR. Relationship between early follow-up and readmission within 30 and 90 days after ischemic stroke. Neurology. 2020 Mar 24;94(12):e1249-e1258. PubMed PMID: 32079738
  • Madsen TE, Khoury JC, Leppert M, Alwell K, Moomaw CJ, Sucharew H, Woo D, Ferioli S, Martini S, Adeoye O, Khatri P, Flaherty M, De Los Rios La Rosa F, Mackey J, Mistry E, Demel SL, Coleman E, Jasne A, Slavin SJ, Walsh K, Star M, Broderick JP, Kissela BM, Kleindorfer DO. Temporal Trends in Stroke Incidence Over Time by Sex and Age in the GCNKSS. Stroke. 2020 Apr;51(4):1070-1076. PubMed PMID: 32078459
  • Pollard R, Case D, Leppert M. No time to delay with large vessel occlusions: Every minute counts. Neurology. 2020 Nov 3;95(18):803-804. PubMed PMID: 32943480
  • Leppert MH, Ho PM, Burke J, Madsen TE, Kleindorfer D, Sillau S, Daugherty S, Bradley CJ, Poisson SN. Young Women Had More Strokes Than Young Men in a Large, United States Claims Sample. Stroke. 2020 Nov;51(11):3352-3355. PubMed PMID: 32942966
  • Salehi Omran S, Leppert MH. Are Strokes Declining Among Pregnant Women With Hypertensive Disorders of Pregnancy?. J Am Heart Assoc. 2020 Aug 4;9(15):e017917. PubMed PMID: 32750293
  • Leppert MH, Sillau S, Lindrooth RC, Poisson SN, Campbell JD, Simpson JR. Relationship between early follow-up and readmission within 30 and 90 days after ischemic stroke. Neurology. 2020 Mar 24;94(12):e1249-e1258. PubMed PMID: 32079738
  • Madsen TE, Khoury JC, Leppert M, Alwell K, Moomaw CJ, Sucharew H, Woo D, Ferioli S, Martini S, Adeoye O, Khatri P, Flaherty M, De Los Rios La Rosa F, Mackey J, Mistry E, Demel SL, Coleman E, Jasne A, Slavin SJ, Walsh K, Star M, Broderick JP, Kissela BM, Kleindorfer DO. Temporal Trends in Stroke Incidence Over Time by Sex and Age in the GCNKSS. Stroke. 2020 Apr;51(4):1070-1076. PubMed PMID: 32078459
  • Mastej EJ, Leppert MH, Poisson S, Ritchey Z, Barry M, Rundek T, Liebeskind DS, Mirsky D, Bernard TJ, Stence NV. Thalamic Volume Loss Is Greater in Children Than in Adults Following Middle Cerebral Artery Territory Arterial Ischemic Stroke. J Child Neurol. 2022 Oct;37(10-11):882-888. PubMed PMID: 36069041
  • Adelman EE, Leppert MH. Advances in Stroke: Neurohospitalist-Inpatient Teleneurology for Longitudinal Stroke Care. Stroke. 2022 May;53(5):1764-1766. PubMed PMID: 35467995
  • Madsen TE, Samaei M, Pikula A, Yu AYX, Carcel C, Millsaps E, Yalamanchili RS, Bencie N, Dula AN, Leppert M, Rundek T, Dreyer RP, Bushnell C. Sex Differences in Physical Activity and Incident Stroke: A Systematic Review. Clin Ther. 2022 Apr;44(4):586-611. PubMed PMID: 35418311
  • Leppert MH, Burke JF, Lisabeth LD, Madsen TE, Kleindorfer DO, Sillau S, Schwamm LH, Daugherty SL, Bradley CJ, Ho PM, Poisson SN. Systematic Review of Sex Differences in Ischemic Strokes Among Young Adults: Are Young Women Disproportionately at Risk?. Stroke. 2022 Feb;53(2):319-327. PubMed PMID: 35073188
  • Adelman EE, Leppert MH. Neurohospitalist: Inpatient Stroke Care in the Time of COVID-19. Stroke. 2021 May;52(5):1871-1873. PubMed PMID: 33874748
  • Huo D, Leppert M, Pollard R, Poisson SN, Fang X, Rubinstein D, Malenky I, Eklund K, Nyberg E. Large Vessel Occlusion Prediction in the Emergency Department with National Institutes of Health Stroke Scale Components: A Machine Learning Approach. J Stroke Cerebrovasc Dis. 2021 Oct;30(10):106030. PubMed PMID: 34403842
  • Poisson SN, Leppert MH, Orjuela KD. Cryptogenic Stroke and PFO Closure: Does Sex Matter?. J Am Heart Assoc. 2023 Oct 3;12(19):e031857. PubMed PMID: 37776208
  • Roopnarinesingh R, Leppert M, Mukherjee D. Evidence And Mechanisms For Embolic Stroke In Contralateral Hemispheres From Carotid Artery Sources. medRxiv. 2023 Aug 23. PubMed PMID: 37162897
  • Adelman EE, Leppert MH. Neuro-Hospitalist-Hospital Capacity Strain Impacting Stroke Care. Stroke. 2023 May;54(5):1390-1391. PubMed PMID: 36951050
  • Mastej EJ, Leppert MH, Poisson S, Ritchey Z, Barry M, Rundek T, Liebeskind DS, Mirsky D, Bernard TJ, Stence NV. Thalamic Volume Loss Is Greater in Children Than in Adults Following Middle Cerebral Artery Territory Arterial Ischemic Stroke. J Child Neurol. 2022 Oct;37(10-11):882-888. PubMed PMID: 36069041
  • Adelman EE, Leppert MH. Advances in Stroke: Neurohospitalist-Inpatient Teleneurology for Longitudinal Stroke Care. Stroke. 2022 May;53(5):1764-1766. PubMed PMID: 35467995
  • Madsen TE, Samaei M, Pikula A, Yu AYX, Carcel C, Millsaps E, Yalamanchili RS, Bencie N, Dula AN, Leppert M, Rundek T, Dreyer RP, Bushnell C. Sex Differences in Physical Activity and Incident Stroke: A Systematic Review. Clin Ther. 2022 Apr;44(4):586-611. PubMed PMID: 35418311
  • Leppert MH, Burke JF, Lisabeth LD, Madsen TE, Kleindorfer DO, Sillau S, Schwamm LH, Daugherty SL, Bradley CJ, Ho PM, Poisson SN. Systematic Review of Sex Differences in Ischemic Strokes Among Young Adults: Are Young Women Disproportionately at Risk?. Stroke. 2022 Feb;53(2):319-327. PubMed PMID: 35073188
  • Leppert MH, Poisson SN, Scarbro S, Suresh K, Lisabeth LD, Putaala J, Schwamm LH, Daugherty SL, Bradley CJ, Burke JF, Ho PM. Association of Traditional and Nontraditional Risk Factors in the Development of Strokes Among Young Adults by Sex and Age Group: A Retrospective Case-Control Study. Circ Cardiovasc Qual Outcomes. 2024 Apr;17(4):e010307. PubMed PMID: 38529631
  • Jellins TS, Borko TL, Otero-Bell R, Arnett K, Saunders S, Poisson SN, Orjuela KD, Salehi Omran S, Jones WJ, Leppert M, Madera A, Carlson A, Pastula DM, Sauer BM, Piquet AL, Gonzales NR. Diversity, equity, and inclusion (DEI) in medical education: DEI at the bedside. J Neurol Sci. 2024 Apr 15;459:122946. PubMed PMID: 38493733
  • Orjuela KD, Leppert MH, Carroll JD. Navigating the Gray: The Complex Story of PFO Closure Utilization. Circ Cardiovasc Qual Outcomes. 2024 Jan;17(1):e010581. PubMed PMID: 38189124
  • Roopnarinesingh R, Leppert M, Mukherjee D. Evidence and Mechanisms for Embolic Stroke in Contralateral Hemispheres From Carotid Artery Sources. J Am Heart Assoc. 2023 Dec 5;12(23):e030792. PubMed PMID: 38014680
  • Poisson SN, Leppert MH, Orjuela KD. Cryptogenic Stroke and PFO Closure: Does Sex Matter?. J Am Heart Assoc. 2023 Oct 3;12(19):e031857. PubMed PMID: 37776208
  • Roopnarinesingh R, Leppert M, Mukherjee D. Evidence And Mechanisms For Embolic Stroke In Contralateral Hemispheres From Carotid Artery Sources. medRxiv. 2023 Aug 23. PubMed PMID: 37162897
  • Adelman EE, Leppert MH. Neuro-Hospitalist-Hospital Capacity Strain Impacting Stroke Care. Stroke. 2023 May;54(5):1390-1391. PubMed PMID: 36951050
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Practice Locations

UCHealth Anschutz Inpatient Pavilion 2 - Anschutz Medical Campus
12505 E. 16th Ave
Aurora, CO 80045
720-848-0000

UCHealth Anschutz Inpatient Pavilion - Anschutz Medical Campus
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Rocky Mountain Regional Veterans Administration Medical Center
1700 Wheeling St
Aurora, CO 80045
303-399-8020

Hospital Affiliation
  • University of Colorado Hospital
  • Veterans Affairs Medical Center

Specialty Information

Specialties
  • Neurology, Board Certification
  • Vascular Neurology
Conditions & Treatments
  • Brain and Nervous System - Stroke
  • Brain and Nervous System

General Information

Medical Schools
  • MD, Emory University School of Medicine (2011)
Graduate Schools
  • MBA, Emory University (2011)
Undergraduate Schools
  • BS, Duke University (NC) (2005)
Internships
  • University of Colorado (University Hospital) Program (2012)
Residency Programs
  • University of Colorado (University Hospital) Program, Neurology(2015)
Fellowships
  • University of Colorado (University Hospital) Program, Vascular Neurology (2016)
Download CV Languages Mandarin
Department Neurology