Vesna Jevtovic-Todorovic, MD, PhD

Professional Titles

• Professor

Research Interests

Developmental Neurotoxicity Pharmacology and mechanisms of chronic pain

Publications

• Jevtovic-Todorovic V. General Anesthetics and Neurotoxicity: How Much Do We Know? Anesthesiol Clin. 2016, 34(3):439-51.
• Milanovic D, Pesic V, Loncarevic-Vasiljkovic N, Pavkovic Z, Popic J, Kanazir S, Jevtovic-Todorovic V, Ruzdijic S. The Fas Ligand/Fas Death Receptor Pathways Contribute to Propofol-Induced Apoptosis and Neuroinflammation in the Brain of Neonatal Rats. Neurotox Res. 2016, 30(3):434-52.
• Dalla Massara L, Osuru HP, Oklopcic A, Milanovic D, Joksimovic SM, Caputo V, DiGruccio MR, Ori C, Wang G, Todorovic SM, Jevtovic-Todorovic V. General Anesthesia Causes Epigenetic Histone Modulation of c-Fos and Brain-derived Neurotrophic Factor, Target Genes Important for Neuronal Development in the Immature Rat Hippocampus. Anesthesiology 2016; 124(6):1311-27.
• Jevtovic-Todorovic V. Anesthetics and Cognitive Impairments in Developing Children: What is Our Responsibility? JAMA Pediatr. 171: 1135-1136, 2017.
• Soriano SG, Vutskits L, Jevtovic-Todorovic V, Hemmings HC. Thinking, fast and slow: highlights from the 2016 BJA seminar on anaesthetic neurotoxicity and neutoplasticity. Br J Anaesth. 119(3):443-447, 2017.
• Jevotovic-Todorovic V. Anaesthesia-induced developmental neurotoxicity: reality or fiction? Br J Anaesth. 119(3):455-457, 2017.
• Jin L, Ding M, Oklopcic A, Aghdasi B, Xiao L, Li Z, Jevtovic-Todorovic V. Nanoparticle fullerol alleviates radiculopathy via NLRP3 inflammasome and neuropeptides. Nanomedicine: Nanotechnology, Biology, and Medicine. 13(6):2049-2059, 2017.
• *Milanovic D, Pesic V, Loncarevic-Vasiljkovic N, Avramovic V, Tesic V, Jevtovic-Todorovic V, Kanazir S, Ruzdijic S. Neonatal Propofol Anesthesia Changes Expression of Synaptic Plasticity Proteins and Increases Stereotypic and Anxyolitic Behavior in Adult Rats. Neurotoxicity Research, 32(2):247-263, 2017.
• Joksimovic SM, Eggan P, Izumi Y, Joksimovic SLj, Tesic V, *Osuru HP, DiGruccio MR, Jevtovic-Todorovic V, Zorumski CF, TodorovicSM. The role of T-channels in the subiculum: to burst or not to burst? J Physiology, 595(19):6327-6348, 2017.
• Jevtovic-Todorovic V, Paule MG. Introduction to the Special Issue "Developmental Neurotoxicity Associated with Pediatric General Anesthesia: Preclinical Findings". Neurotoxicol Teratol, 2017.
• *Weaver J, Arandjelovic S, Brown G, Mendu S, Schappe M, Buckley M, Chiu Y-H, Shu S, Kim J, Chung J, Krupa J, Jevtovic-Todorovic V, Desai B, Ravichandran K, Bayliss DA. Hematopoietic pannexin 1 function is critical for neuropathic pain. Sci Rep. 7: 42550, 2017.
• *Zanghi CN, Jevtovic-Todorovic V. A holistic approach to anesthesia-induced neurotoxicity and its implications for future mechanistic studies. Neurotoxicol Teratol. 60:24-32, 2017.
• Joksimovic SL, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Neurosteroids in Pain Management: A New Perspective on an Old Player. Front Pharmacol. 2018;9:1127. PubMed PMID: 30333753
• Joksimovic SL, Joksimovic SM, Tesic V, García-Caballero A, Feseha S, Zamponi GW, Jevtovic-Todorovic V, Todorovic SM. Selective inhibition of Ca(V)3.2 channels reverses hyperexcitability of peripheral nociceptors and alleviates postsurgical pain. Sci Signal. 2018 Aug 28;11(545). PubMed PMID: 30154101
• Vutskits L, Sall JW, Jevtovic-Todorovic V. A poisoned chalice: the heritage of parental anaesthesia exposure. Br J Anaesth. 2018 Aug;121(2):337-339. PubMed PMID: 30032869
• Tracy ME, Tesic V, Stamenic TT, Joksimovic SM, Busquet N, Jevtovic-Todorovic V, Todorovic SM. Ca(V)3.1 isoform of T-type calcium channels supports excitability of rat and mouse ventral tegmental area neurons. Neuropharmacology. 2018 Jun;135:343-354. PubMed PMID: 29578032
• Atluri N, Joksimovic SM, Oklopcic A, Milanovic D, Klawitter J, Eggan P, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V. A neurosteroid analogue with T-type calcium channel blocking properties is an effective hypnotic, but is not harmful to neonatal rat brain. Br J Anaesth. 2018 Apr;120(4):768-778. PubMed PMID: 29576117
• Jevtovic-Todorovic V. Monkey business: the importance of mounting behavioural evidence for anaesthesia-induced developmental neurotoxicity. Br J Anaesth. 2018 Apr;120(4):617-619. PubMed PMID: 29576100
• Maloney SE, Creeley CE, Hartman RE, Yuede CM, Zorumski CF, Jevtovic-Todorovic V, Dikranian K, Noguchi KK, Farber NB, Wozniak DF. Using animal models to evaluate the functional consequences of anesthesia during early neurodevelopment. Neurobiol Learn Mem. 2018 Mar 14. [Epub ahead of print] PubMed PMID: 29550366
• Jevtovic-Todorovic V. Exposure of Developing Brain to General Anesthesia: What Is the Animal Evidence?. Anesthesiology. 2018 Apr;128(4):832-839. PubMed PMID: 29271804
• Joksimovic SM, Osuru HP, Oklopcic A, Beenhakker MP, Jevtovic-Todorovic V, Todorovic SM. Histone Deacetylase Inhibitor Entinostat (MS-275) Restores Anesthesia-induced Alteration of Inhibitory Synaptic Transmission in the Developing Rat Hippocampus. Mol Neurobiol. 2018 Jan;55(1):222-228. PubMed PMID: 28840475
• Obradovic AL, Atluri N, Dalla Massara L, Oklopcic A, Todorovic NS, Katta G, Osuru HP, Jevtovic-Todorovic V. Early Exposure to Ketamine Impairs Axonal Pruning in Developing Mouse Hippocampus. Mol Neurobiol. 2018 Jan;55(1):164-172. PubMed PMID: 28840469
• Jevtovic-Todorovic V, Brambrick A. General Anesthesia and Young Brain: What is New?. J Neurosurg Anesthesiol. 2018 Jul;30(3):217-222. PubMed PMID: 28622158
• Jevtovic-Todorovic V, Vutskits L. Beyond Anesthesia Apoptosis: Wiring and Communication Matter!. Anesthesiology. 2020 Sep;133(3):495-496. PubMed PMID: 32788555
• Tesic V, Joksimovic SM, Quillinan N, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V. Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABA(A) currents, but are not neurotoxic to the developing rat brain. Br J Anaesth. 2020 May;124(5):603-613. PubMed PMID: 32151384
• Chinn GA, Pearn ML, Vutskits L, Mintz CD, Loepke AW, Lee JJ, Chen J, Bosnjak ZJ, Brambrink AM, Jevtovic-Todorovic V, Sun LS, Sall JW. Standards for preclinical research and publications in developmental anaesthetic neurotoxicity: expert opinion statement from the SmartTots preclinical working group. Br J Anaesth. 2020 May;124(5):585-593. PubMed PMID: 32145876
• Cabrera OH, Gulvezan T, Symmes B, Quillinan N, Jevtovic-Todorovic V. Sex differences in neurodevelopmental abnormalities caused by early-life anaesthesia exposure: a narrative review. Br J Anaesth. 2020 Mar;124(3):e81-e91. PubMed PMID: 31980157
• Chastain-Potts SE, Tesic V, Tat QL, Cabrera OH, Quillinan N, Jevtovic-Todorovic V. Sevoflurane Exposure Results in Sex-Specific Transgenerational Upregulation of Target IEGs in the Subiculum. Mol Neurobiol. 2020 Jan;57(1):11-22. PubMed PMID: 31512116
• Diana P, Joksimovic SM, Faisant A, Jevtovic-Todorovic V. Early exposure to general anesthesia impairs social and emotional development in rats. Mol Neurobiol. 2020 Jan;57(1):41-50. PubMed PMID: 31494825
• Cabrera OH, Tesic V, Tat QL, Chastain S, Quillinan N, Jevtovic-Todorovic V. Sevoflurane-Induced Dysregulation of Cation-Chloride Cotransporters NKCC1 and KCC2 in Neonatal Mouse Brain. Mol Neurobiol. 2020 Jan;57(1):1-10. PubMed PMID: 31493242
• Joksimovic SM, DiGruccio MR, Boscolo A, Jevtovic-Todorovic V, Todorovic SM. The Role of Free Oxygen Radicals in Lasting Hyperexcitability of Rat Subicular Neurons After Exposure to General Anesthesia During Brain Development. Mol Neurobiol. 2020 Jan;57(1):208-216. PubMed PMID: 31493241
• Joksimovic SL, Joksimovic SM, Manzella FM, Asnake B, Orestes P, Raol YH, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Novel neuroactive steroid with hypnotic and T-type calcium channel blocking properties exerts effective analgesia in a rodent model of post-surgical pain. Br J Pharmacol. 2020 Apr;177(8):1735-1753. PubMed PMID: 31732978
• Manzella FM, Joksimovic SM, Orfila JE, Fine BR, Dietz RM, Sampath D, Fiedler HK, Tesic V, Atluri N, Raol YH, Jevtovic-Todorovic V, Herson PS, Todorovic SM. Neonatal Ketamine Alters High-Frequency Oscillations and Synaptic Plasticity in the Subiculum But Does not Affect Sleep Macrostructure in Adolescent Rats. Front Syst Neurosci. 2020;14:26. PubMed PMID: 32528257
• Joksimovic SM, Izumi Y, Joksimovic SL, Tesic V, Krishnan K, Asnake B, Jevtovic-Todorovic V, Covey DF, Zorumski CF, Todorovic SM. Novel neurosteroid hypnotic blocks T-type calcium channel-dependent rebound burst firing and suppresses long-term potentiation in the rat subiculum. Br J Anaesth. 2019 May;122(5):643-651. PubMed PMID: 30916017
• Woodward TJ, Tesic V, Stamenic TT, Jevtovic-Todorovic V, Todorovic SM. Pharmacological Antagonism of T-Type Calcium Channels Constrains Rebound Burst Firing in Two Distinct Subpopulations of GABA Neurons in the Rat Ventral Tegmental Area: Implications for a-Lipoic Acid. Front Pharmacol. 2019;10:1402. PubMed PMID: 31849661
• Tat QL, Joksimovic SM, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V. Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels. Cells. 2020 Dec 12;9(12). PubMed PMID: 33322727
• Timic Stamenic T, Feseha S, Manzella FM, Wallace D, Wilkey D, Corrigan T, Fiedler H, Doerr P, Krishnan K, Raol YH, Covey DF, Jevtovic-Todorovic V, Todorovic SM. The T-type calcium channel isoform Ca(v)3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3ß,5ß,17ß)-3-hydroxyandrostane-17-carbonitrile. Br J Anaesth. 2020 Aug 25. [Epub ahead of print] PubMed PMID: 32859366
• Joksimovic SL, Evans JG, McIntire WE, Orestes P, Barrett PQ, Jevtovic-Todorovic V, Todorovic SM. Glycosylation of Ca(V)3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes. Front Cell Neurosci. 2020;14:605312. PubMed PMID: 33384586
• 1. Tat QL, Joksimovic SM, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V. Preemptive Analgesic Effect of Intrathecal Applications of Neuroactive Steroids in a Rodent Model of Post-Surgical Pain: Evidence for the Role of T-Type Calcium Channels. Cells 2020, 9: 2674-2686.
• 2. Joksimovic SL, Evans JG, McIntire WE, Orestes P, Barrett PQ, Jevtovic-Todorovic V, Todorovic SM. Glycosylation of CaV3.2 Channels Contributes to the Hyperalgesia in Peripheral Neuropathy of Type 1 Diabetes. Front Cell Neurosci. 2020 15;14:605312.
• Jevtovic-Todorovic V. Sex hormones and the young brain: are we ready to embrace neuroprotective strategies? Br J Anaesth. 2021, in press.
• Manzella FM, Gulvezan BF, *Maksimovic S, *Useinovic N, Raol YH, Joksimovic SM, Jevtovic-Todorovic V, Todorovic SM Neonatal Isoflurane Does Not Affect Sleep Architecture and Minimally Alters Neuronal Beta Oscillations in Adolescent Rats. Front Behav Neurosci. 2021, 15:703859.
• Penning DH, Cazacu S, Brodie A, Jevtovic-Todorovic V, Kalkanis SN, Lewis M, Brodie C. Neuron-Glia Crosstalk Plays a Major Role in the Neurotoxic Effects of Ketamine via Extracellular Vesicles. Front Cell Dev Biol. 2021, 9: 691648.
• 3. Timic Stamenic T, Feseha S, Manzella FM, Wallace D, Wilkey D, Corrigan T, Fiedler H, Doerr P, Krishnan K, Raol YH, Covey DF, Jevtovic-Todorovic V, Todorovic SM. The T-type calcium channel isoform Cav3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3ß,5ß,17ß)-3-hydroxyandrostane-17-carbonitrile. Br J Anaesth. 2020, S0007-0912 (20)30611-5.
• *Cabrera OH, *Useinovic N, Jevtovic-Todorovic V. Neonatal Anesthesia and dysregulation of the Epigenome. Biol Reprod. 2021, 105(3):720-734.
• Joksimovic SL, Lamborn N, Jevtovic-Todorovic V, Todorovic SM. Alpha lipoic acid attenuates evoked and spontaneous pain following surgical skin incision in rats. Channels 2021 15: 398-407.
• Joksimovic SM, Sampath D, Krishnan K, Covey DF, Jevtovic-Todorovic V, Raol YH, Todorovic SM. Differential effects of the novel neurosteroid hypnotic (3ß,5ß,17ß)-3-hydroxyandrostane-17-carbonitrile on electroencephalogram activity in male and female rats. Br J Anaesth. 2021, in press.
• Jevtovic-Todorovic V. Detrimental effects of general anaesthesia on young primates: are we closer to understanding the link? Br J Anaesth. 2021 126: 575-577.
• 4. Jevtovic-Todorovic V, Vutskits L. Beyond Anesthesia Apoptosis: Wiring and Communication Matter! Anesthesiology 2020, 133(3):495-496.
• 5. Manzella FM, Joksimovic SM, Orfila JE, Fine BR, Dietz RM, Sampath D, Fiedler HK, *Tesic V, *Atluri N, Raol YH, Jevtovic-Todorovic V, Herson PS, Todorovic SM. Neonatal Ketamine Alters High-Frequency Oscillations and Synaptic Plasticity in the Subiculum But Does not Affect Sleep Macrostructure in Adolescent Rats. Front Syst Neurosci. 2020, 14:26.
• 6. *Tesic V, Joksimovic SM, Quillinan N, Krishnan K, Covey DF, Todorovic SM, Jevtovic-Todorovic V. Neuroactive steroids alphaxalone and CDNC24 are effective hypnotics and potentiators of GABAA currents, but are not neurotoxic to the developing rat brain. Br J Anaesth. 2020, 124(5): 603-613.
• Anesthesia and Cancer, Friend or Foe? A Narrative Review. Montejano J, Jevtovic-Todorovic V. Front Oncol. 2021 Dec 23;11:803266. doi: 10.3389/fonc.2021.803266. eCollection 2021. PMID: 35004329
• Synthetic neuroactive steroids as new sedatives and anaesthetics: Back to the future. Manzella FM, Covey DF, Jevtovic-Todorovic V, Todorovic SM. J Neuroendocrinol. 2021 Dec 30:e13086. doi: 10.1111/jne.13086. Online ahead of print. PMID: 35014105
• The T-type calcium channel isoform Cav3.1 is a target for the hypnotic effect of the anaesthetic neurosteroid (3ß,5ß,17ß)-3-hydroxyandrostane-17-carbonitrile. Timic Stamenic T, Feseha S, Manzella FM, Wallace D, Wilkey D, Corrigan T, Fiedler H, Doerr P, Krishnan K, Raol YH, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Br J Anaesth. 2021 Jan;126(1):245-255. doi: 10.1016/j.bja.2020.07.022. Epub 2020 Aug 25. PMID: 32859366
• 7. Chinn GA, Pearn ML, Vutskits L, Mintz CD, Loepke AW, Lee JJ, Chen J, Bosnjak ZJ, Brambrink AM, Jevtovic-Todorovic V, Sun LS, Sall JW. Standards for preclinical research and publications in developmental anaesthetic neurotoxicity: expert opinion statement from the SmartTots preclinical working group. Br J Anaesth. 2020, 124(5): 585-593.
• 8. *Cabrera OH, *Gulvezan T, *Symmes B, Quillinan N, Jevtovic-Todorovic V. Sex differences in neurodevelopmental abnormalities caused by early-life anaesthesia exposure: a narrative review. Br J Anaesth. 2020;124(3): e81-e91.
• Jevtovic-Todorovic V, Todorovic SM. The Role of Neuroactive Steroids in Analgesia and Anesthesia: An Interesting Comeback?. Biomolecules. 2023 Nov 15;13(11). PubMed PMID: 38002336
• Useinovic N, Near M, Cabrera OH, Boscolo A, Milosevic A, Harvey R, Newson A, Chastain-Potts S, Quillinan N, Jevtovic-Todorovic V. Neonatal sevoflurane exposure induces long-term changes in dendritic morphology in juvenile rats and mice. Exp Biol Med (Maywood). 2023 Apr;248(7):641-655. PubMed PMID: 37309741
• Fine-Raquet B, Manzella FM, Joksimovic SM, Dietz RM, Orfila JE, Sampath D, Tesic V, Atluri N, Covey DF, Raol YH, Jevtovic-Todorovic V, Herson PS, Todorovic SM. Neonatal exposure to a neuroactive steroid alters low-frequency oscillations in the subiculum. Exp Biol Med (Maywood). 2023 Apr;248(7):578-587. PubMed PMID: 37309730
• Useinovic N, Jevtovic-Todorovic V. Controversies in anesthesia-induced developmental neurotoxicity. Best Pract Res Clin Anaesthesiol. 2023 Mar;37(1):28-39. PubMed PMID: 37295851
• Jevtovic-Todorovic V, Useinovic N. Early exposure to general anaesthesia and increasing trends in developmental behavioural impairments: is there a link?. Br J Anaesth. 2023 Aug;131(2):208-211. PubMed PMID: 37173202
• Joksimovic SM, Ghodsi SM, Heinsbroek JA, Orfila JE, Busquet N, Tesic V, Valdez R, Fine-Raquet B, Jevtovic-Todorovic V, Raol YH, Herson PS, Todorovic SM. Ca(V)3.1 T-type calcium channels are important for spatial memory processing in the dorsal subiculum. Neuropharmacology. 2023 Mar 15;226:109400. PubMed PMID: 36586474
• Manzella FM, Cabrera OH, Wilkey D, Fine-Raquet B, Klawitter J, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Sex-specific hypnotic effects of the neuroactive steroid (3ß,5ß,17ß)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid. Br J Anaesth. 2023 Feb;130(2):154-164. PubMed PMID: 36428160
• Joksimovic SM, Ghodsi SM, Heinsbroek JA, Orfila JE, Busquet N, Tesic V, Valdez R, Fine-Raquet B, Jevtovic-Todorovic V, Raol YH, Herson PS, Todorovic SM. Ca(V)3.1 T-type calcium channels are important for spatial memory processing in the dorsal subiculum. Neuropharmacology. 2022 Dec 29;226:109400. [Epub ahead of print] PubMed PMID: 36586474
• Manzella FM, Cabrera OH, Wilkey D, Fine-Raquet B, Klawitter J, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Sex-specific hypnotic effects of the neuroactive steroid (3ß,5ß,17ß)-3-hydroxyandrostane-17-carbonitrile are mediated by peripheral metabolism into an active hypnotic steroid. Br J Anaesth. 2023 Feb;130(2):154-164. PubMed PMID: 36428160
• Cabrera OH, Useinovic N, Maksimovic S, Near M, Quillinan N, Todorovic SM, Jevtovic-Todorovic V. Neonatal ketamine exposure impairs infrapyramidal bundle pruning and causes lasting increase in excitatory synaptic transmission in hippocampal CA3 neurons. Neurobiol Dis. 2022 Dec;175:105923. PubMed PMID: 36371060
• Simmons CG, Alvey NJ, Kaizer AM, Williamson K, Faruki AA, Kacmar RM, Jevtovic-Todorovic V, Weitzel NS. Correction to: Benchmarking of Anesthesia and Surgical Control Times by Current Procedural Terminology (CPT®) Codes. J Med Syst. 2022 Aug 11;46(9):60. PubMed PMID: 35951122
• Joksimovic SL, Jevtovic-Todorovic V, Todorovic SM. The role of voltage-gated calcium channels in the mechanisms of anesthesia and perioperative analgesia. Curr Opin Anaesthesiol. 2022 Aug 1;35(4):436-441. PubMed PMID: 35787588
• Useinovic N, Jevtovic-Todorovic V. Novel anesthetics in pediatric practice: is it time?. Curr Opin Anaesthesiol. 2022 Aug 1;35(4):425-435. PubMed PMID: 35787582
• Useinovic N, Maksimovic S, Liechty C, Cabrera OH, Quillinan N, Jevtovic-Todorovic V. Systemic inflammation exacerbates developmental neurotoxicity induced by sevoflurane in neonatal rats. Br J Anaesth. 2022 Oct;129(4):555-566. PubMed PMID: 35701270
• Timic Stamenic T, Manzella FM, Maksimovic S, Krishnan K, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Further Evidence that Inhibition of Neuronal Voltage-Gated Calcium Channels Contributes to the Hypnotic Effect of Neurosteroid Analogue, 3ß-OH. Front Pharmacol. 2022;13:850658. PubMed PMID: 35677453
• Saric N, Hashimoto-Torii K, Jevtovic-Todorovic V, Ishibashi N. Nonapoptotic caspases in neural development and in anesthesia-induced neurotoxicity. Trends Neurosci. 2022 Jun;45(6):446-458. PubMed PMID: 35491256
• Joksimovic SL, Jevtovic-Todorovic V, Todorovic SM. The Mechanisms of Plasticity of Nociceptive Ion Channels in Painful Diabetic Neuropathy. Front Pain Res (Lausanne). 2022;3:869735. PubMed PMID: 35419564
• Simmons CG, Alvey NJ, Kaizer AM, Williamson K, Faruki AA, Kacmar RM, Jevtovic-Todorovic V, Weitzel NS. Benchmarking of Anesthesia and Surgical Control Times by Current Procedural Terminology (CPT®) Codes. J Med Syst. 2022 Mar 4;46(4):19. PubMed PMID: 35244783
• Maksimovic S, Useinovic N, Quillinan N, Covey DF, Todorovic SM, Jevtovic-Todorovic V. General Anesthesia and the Young Brain: The Importance of Novel Strategies with Alternate Mechanisms of Action. Int J Mol Sci. 2022 Feb 8;23(3). PubMed PMID: 35163810
• Useinovic N, Maksimovic S, Near M, Quillinan N, Jevtovic-Todorovic V. Do We Have Viable Protective Strategies against Anesthesia-Induced Developmental Neurotoxicity?. Int J Mol Sci. 2022 Jan 20;23(3). PubMed PMID: 35163060
• Jevtovic-Todorovic V. Testosterone: much more for the brain than a sex hormone. Br J Anaesth. 2022 Mar;128(3):411-413. PubMed PMID: 35115156
• Manzella FM, Covey DF, Jevtovic-Todorovic V, Todorovic SM. Synthetic neuroactive steroids as new sedatives and anaesthetics: Back to the future. J Neuroendocrinol. 2022 Feb;34(2):e13086. PubMed PMID: 35014105
• Jevtovic-Todorovic V. Sex hormones and the young brain: are we ready to embrace neuroprotective strategies?. Br J Anaesth. 2022 Feb;128(2):229-231. PubMed PMID: 34857358

Practice Locations

UCHealth University of Colorado Hospital (UCH)
12605 E. 16th Ave
Aurora, CO 80045
720-848-0000

Hospital Affiliation

• University of Colorado Hospital

Center Affiliations

• Center for Neuroscience

Specialty Information

Specialties

• Anesthesiology, Board Certification