Professor, Anesthesiology-Pediatric Anesthesiology
Medical School
MB ChB, University Of the Witwatersrand, Johannesburg, South Africa
(1988)
Internship
Johannesburg General Hospital
(1989)
Residency
University Of the Witwatersrand, Johannesburg, South Africa, Anesthesiology (1995)
LanguagesEnglish Department
Anesthesiology-Pediatric Anesthesiology
Professional Titles
Director of Clinical Research Anesthesiology
Publications
Twite MD, Ing RJ. Tetralogy of Fallot: Peri-operative anesthetic management of children and adults. Semin Cardiothorac Vasc Anesth. 2012 Jan 24. [Epub ahead of print] PMID: 22275349
Ing RJ, Ames WA, Chambers NS. Paediatric cardiomyopathy and anaesthesia. Br J Anaesth. 2012 Jan;108(1):4-12. PMID: 22157445
McRobb C, Walczak R, S Lawson S, A Lodge AJ, Lockhart E, N Bandarenko III N, Ing RJ. Carboxyhemoglobinemia in a Pediatric Cardiopulmonary Bypass Patient Derived from a Contaminated Unit of Allogenic Blood. Perfusion. 2011 Jul; 26 (4):302-7. PMID: 21593087
Fahy CJ, Ing RJ, Kern FH, O’Hare B, JM Redmond, Jaggers J. The anaesthetic management and physiological implications in infants with anomalous left coronary artery arising from the pulmonary artery: A report of two cases and review. Jnl Cardiothoracic and Vasc Anesthesia Mar 25 2011. PMID: 21441041
Ing RJ, Ross A. Anesthesia for the extremely low birthweight infant. Pediatric Anesthesia: Basic Principles, State-of-the-Art, Future. Edited by Bruno Bissonnett. Sub editors: Drs Joseph Tobias, Brian Anderson, Bruno Marciniak, Adrian Bosenberg, Linda Mason and Thomas Engelhardt. Published September 2011. ISBN-13: 978-1607950936
Twite MD, Ing RJ. Anesthetic Considerations in Infants with Hypoplastic Left Heart Syndrome. Semin Cardiothorac Vasc Anesth. 2013 Feb 14. PMID: 23416713
Singhal N, da Cruz EM, Nicolarsen J, Schwartz L, Merritt G, Barrett C, Twite, M, Ing RJ. Perioperative management of shock in two Fontan patients with plastic bronchitis. Semin Cardiothorac Vasc Anesth. 17 Issue 1 March 2013 pp. 55 - 60. PMID: 23381614
Ing RJ, Fahy CJ. Response to Drs Neema and Rathod. J Cardiothorac Vasc Anesth. 2012 Jul 11.
PMID: 22795173.
Singhal N, da Cruz EM, Nicolarsen J, Schwartz L, Merritt G, Barrett C, Twite, M, Ing RJ. Perioperative management of shock in two Fontan patients with plastic bronchitis. Semin Cardiothorac Vasc Anesth. 2013 Mar; 17(1):55-60. PMID: 23381614
Twite MD, Ing RJ. Anesthetic Considerations in Infants with Hypoplastic Left Heart Syndrome. Semin Cardiothorac Vasc Anesth. 2013 Jun; 17 (2):137-45. PMID: 23416713
Kaufmann J, Twite M, Barrett C, Peyton C, Koehler J, Rannie M, Kahn MG, Schofield S, Ing RJ, Jaggers J, Hyman D, da Cruz EM. A handoff protocol from the cardiovascular operating room to cardiac ICU is associated with improvements in care beyond the immediate postoperative period. Jt Comm J Qual Patient Saf. 2013 Jul; 39 (7):306-11. PMID:23888640
Mejak BL, Ing RJ, McRobb, C, Ellis WC, Lawson D. S, Twite MD, Jaggers, J. Cryoprecipitate and platelet administration during modified ultrafiltration in children less than 10 kg undergoing cardiac surgery. J Extra Corpor Technol. 2013 Jun; 45(2):107-11. PMID:23930379
Ing RJ, Craig DM, Nowosad A, Twite MD, B?senberg AT. Anaesthetic Safety of the Macintosh Oral Laryngeal Spray Device. South Afr J Anaesth Analg 2013;19(4)212-215
Krieves MA, Merritt GR, Nichols C, Schwartz LI, Campbell DN, Bruny JL, Fagan TE, Thompson ME, Ing RJ. Aortoesophageal Fistula and Coarctation of the Aorta in a 15 year old child. Semin Cardiothorac Vasc Anesth. 2013 Dec;17(4):294-7 PMID:24122581
3. Fagan T, Eisdorfer S, Landeck B, Howley L, Aldoss O, Twite M, Jaggers J, Ing RJ. Interventional cardiac catheterization management of a newborn infant with hypoplastic left heart syndrome, cor-triatriatum and aberrant pulmonary veins with an obstructed vertical vein to the superior vena cava. Interventional Cardiology. 2014 June 6(3),265-270.
Truong UT, Fagan TE, Deterding R, Ing RJ, Fonseca BM. Use of rotational angiography in assessing relationship of the airway to vasculature during cardiac catheterization. Catheter Cardiovasc Interv. 2015 Nov 15;86(6):1068-77. PubMed PMID: 26279410
Ngo KD, Pian P, Hanfland R, Nichols CS, Merritt GR, Campbell D, Ing RJ. Cardiac Injury After All-Terrain Vehicle Accidents in 2 Children and a Review of the Literature. Pediatr Emerg Care. 2015 Oct 13. [Epub ahead of print] PubMed PMID: 26466145
Clopton RG, Friesen RH, Partrick DA, Wilson N, Jaggers J, Ivy D, Schwartz LI, Ing RJ. The Anesthetic Challenges of Lung Biopsy–Associated Intrathoracic Hemorrhage in a Child with Suprasystemic Pulmonary Hypertension. Seminars in Cardiothoracic and Vasc Anesthesia Nov 3. 2016 DOI: 10.1177/1089253216672011 PMID: 27815350
Ing RJ, Mayes L, Kramer R, Darst J, Twite M. Button Battery Ingestion in Children: a role for angiography? Canadian Journal of Anesthesia. 1 Nov 2016 PMID:27804024
McRobb CM, Ing RJ, Lawson DS, Jaggers J, Twite M. Retrospective analysis of eliminating modified ultrafiltration after pediatric cardiopulmonary bypass. Perfusion. 2016 Oct 5. PMID: 27708000.
Ing RJ. Update on neurotoxicity of anesthetic agents in the immature brain. South Afr J Anaesth Analg 2016; 22(1) Supplement 3: S17-S20.
Merritt GR, Barrett C, Capocelli KE, Krieves M, Jhajj S, McRobb C, Jaggers J, Ing RJ. Clinical management of neonatal massive hemolysis during cardiopulmonary bypass. J Clin Anesthesiol 2016: 4(1): 1049. ISSN: 2333-6641
Twite M, Ing RJ. Noteworthy Literature in 2015: Anesthesia for Congenital Heart Disease.
Semin Cardiothorac Vasc Anesth. 2016 Mar;20(1):14-23. PMID: 26783264.
Ngo K, Phan P, Hanfland R, Nichols CS, Merritt GR , Campbell DN, Ing RJ Cardiac injury following all-terrain vehicle accidents in two children and a review of the literature. Pediatric Emergency Care Medicine. 2016 Jul;32(7):468-71. PMID: 26466145.
Jone PN, Tapia D, Davidson J, Fagan TE, Browne L, Ing RJ, Kay J. Successful Treatment of Myocardial Infarction in an Infant With Kawasaki Disease. Semin Cardiothorac Vasc Anesth. 2015 Sep;19(3):255-9. PubMed PMID: 25700695
Ing RJ, Twite MD. The year in review: anesthesia for congenital heart disease 2014. Semin Cardiothorac Vasc Anesth. 2015 Mar;19(1):12-20. PubMed PMID: 25667304
Friesen RH, Slavov D, Miyamoto SD, Ing RJ, LaRiviere WB, Matthew R. G. Taylor MRG. Lack of Association of Vasoconstriction Response to Dexmedetomidine with Adrenoreceptor Genotype. Semin Cardiothorac Vasc Anesth. May 8 2017. DOI: 10.1177/1089253217708621
Echaniz G, De Miguel M, Merritt G, Sierra P, Bora P, Borah N, Ciarallo C, de Nadal M, Ing RJ, Bosenberg A. Bilateral suprazygomatic maxillary nerve blocks vs. infraorbital and palatine nerve blocks in cleft lip and palate repair: A double-blind prospective, randomised study. Eur J Anaesthesiol. 2018 Oct 10. [Epub ahead of print] PubMed PMID: 30308523
Stone M, Ing RJ. Transthoracic Ventricular Septal Defect Closure in Children: An Evolving Treatment Strategy as an Alternative to Open Surgical Repair. J Cardiothorac Vasc Anesth. 2018 Aug 7. [Epub ahead of print] PubMed PMID: 30217586
Schäfer M, Wilson N, Ivy DD, Ing R, Abman S, Browne LP, Morgan G, Ross M, McLennan D, Barker AJ, Fonseca B, Di Maria M, Hunter KS, Truong U. Noninvasive wave intensity analysis predicts functional worsening in children with pulmonary arterial hypertension. Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H968-H977. PubMed PMID: 30004811
Ing RJ, Twite MD. Toward Improved Neurodevelopmental Outcomes: The Role of Transfontanel Ultrasound Assessment of Cerebral Blood Flow in Infants Undergoing Cardiac Surgery. J Cardiothorac Vasc Anesth. 2018 Aug;32(4):1655-1656. PubMed PMID: 29501227
Ing RJ, Twite MD. Noteworthy Literature published in 2017 for Congenital Cardiac Anesthesiologists. Semin Cardiothorac Vasc Anesth. 2018 Mar;22(1):35-48. PubMed PMID: 29400257
Ing RJ, Hoagland M, Mayes L, Twite M. The anesthetic management of button battery ingestion in children. Can J Anaesth. 2018 Mar;65(3):309-318. PubMed PMID: 29168156
Ing RJ, Twite M, Barrett C. Review of the Society of Thoracic Surgeons Congenital Heart Surgery Database: 2017 Update on Outcomes and Quality Implications for the Anesthesiologist. J Cardiothorac Vasc Anesth. 2017 Dec;31(6):1934-1938. PubMed PMID: 29107588
Ing RJ, Stone M. Optimal positioning of the inferior vena cava cannula during cardiac surgery in children. J Cardiothorac Vasc Anesth. 2019 May;33(5):1260-12. PMID: 30655201
Mejak B, Lawson DS, Ing RJ. Con: Modified Ultrafiltration in Pediatric Cardiac Surgery Is No Longer Necessary. In Press. J Cardiothorac Vasc Anesth. 2019 Mar;33(3):870-872. PMID: 30587424.
Hoagland MA, Ing RJ, Jatana KR, Jacobs IN, Chatterjee D. Review: Anesthetic Implications of the New Guidelines on Button Battery Ingestion in Children. Anesthesia & Analgesia 2019 Feb 27. PMID: 30829672.
Ing RJ, Twite M. The Year in Review: Anesthesia for Congenital Heart Disease 2018. Semin Cardiothorac Vasc Anesth. 2019 Jun;23(2):205-211. PMID: 31064317
Chatterjee D, Ing RJ, Gien J. Update on Congenital Diaphragmatic Hernia. Anesthesia & Analgesia. 2019 Jul 17. PMID: 31335403
Twite MD, Stenquist S, Ing RJ. Williams syndrome. Pediatric Anesthesia 2019 May; 29(5): 483-490. PMID 30811742
Davidson JA, Khailova L, Treece A, Robison J, Soranno DE, Jaggers J, Ing RJ, Lawson S, Osorio Lujan S. Alkaline phosphatase treatment of Acute Kidney injury in an infant piglet Model of cardiopulmonary Bypass with Deep Hypothermic Circulatory Arrest. Scientific Reports Nature (2019) 9:14175 PMID: 31578351
Khailova L, Robison J, Jaggers J, Ing RJ, Lawson S, Treece A, Soranno D, Osorio Lujan S, Davidson JA. Tissue alkaline phosphatase activity and expression in an experimental infant swine model of cardiopulmonary bypass with deep hypothermic circulatory arrest. J Inflamm (Lond) 2020; 17: 27. Published online 2020 Aug 12. doi: 10.1186/s12950-020-00256-2. PMCID: PMC7422466.
Censoplano NM, Barrett CS, Ing RJ, Reichert K, Rannie M, Kaufman J. Achieving Sustainability in Reducing Unplanned Extubations in a Pediatric Cardiac ICU. Pediatr Crit Care Med. 2020 Apr;21(4):350-356. doi: 10.1097/PCC.0000000000002193. PMID: 31688673
Zacherie R. Conover ZR, Talai A, Klockau KS, Ing RJ, Chatterjee D. Perioperative Management of Children on Ketogenic Dietary Therapies. Anesth and Analg Anesth Analg 2020 doi: 10.1213/ANE.0000000000005018. PMID: 32769381
Ing RJ, Mclennan D, Twite MD, DiMaria M. Anesthetic Considerations for Fontan-Associated Liver Disease and the Failing Fontan Circuit. J Cardiothorac Vasc Anesth. 2020 Feb 29. doi: 10.1053/j.jvca.2020.02.040. PMID: 32249074
Houska N, Twite MD, Ing RJ. The Importance of the Airway in Children Undergoing Surgery for Congenital Heart Disease. J Cardiothorac Vasc Anesth 2020 Sep 10; S1053-0770(20)30995-2. DOI: 10.1053/j.jvca.2020.09.089 PMID: 33004270
Ing RJ, Chatterjee D, Twite MD. Resuscitating Children with COVID-19: What the Pediatric Anesthesiologist Needs to Know. J Cardiothorac Vasc Anesth. 2020 Jun 16: doi: 10.1053/j.jvca.2020.06.037. PMID: 32624434.
Ing RJ, Bills C, Merritt G, Ragusa R, Bremner RM, Bellia F. The role of helmet-delivered noninvasive pressure support ventilation in COVID-19 patients. J Cardiothorac Vasc Anesth. 2020 May 8 doi: 0.1053/j.jvca.2020.04.060 [Epub ahead of print] PMCID: PMC7205670
Stone M, Choi R, Ing, RJ. Optimization of Right Internal Jugular central venous catheter length in pediatric cardiac surgical patients Accepted in press J Cardiothorac Vasc Anesth J Cardiothorac Vasc Anesth. 2020 Sep;34(9):2392-2394. doi: 10.1053/j.jvca.2020.04.034. PMID: 32534878
Schafer M, Truong U, Browne L, Morgan G; Michael Ross M, Ing RJ, Kendall Hunter K, Kheyfets
V, Abman S, Dunbar Ivy D, Wilson N. Measuring Flow Hemodynamic Indices and Oxygen Consumption in Children with Pulmonary Hypertension: A Comparison of Catheterization and Phase-Contrast MRI" Accepted minor revisions Pediatric Cardiology Sept 2017 PEDC-D-17-00404.
McRobb CM, Ing RJ, Lawson DS, Jaggers J, Twite M. Retrospective analysis of eliminating modified ultrafiltration after pediatric cardiopulmonary bypass. Perfusion. 2017 Mar; 32(2):97-109 PMID: 27708000.
Fritock, M, Ing RJ, Twite M. Cardiac Arrest in two neonates receiving Amiodarone and Dexmedetomidine: Journal of Cardiothoracic and Vascular Anesthesia. February 2017. doi: 10.1053/j.jvca.2017.02.176 PMID: 28550956
Schäfer M, Frank BS, Ivy DD, Abman SH, Stenmark KR, Mitchell MB, Browne LP, Barker AJ, Hunter KS, Kheyfets V, Miller-Reed K, Ing RJ, Morgan GJ, Truong U. Short-Term Effects of Inhaled Nitric Oxide on Right Ventricular Flow Hemodynamics by 4-Dimensional-Flow Magnetic Resonance Imaging in Children With Pulmonary Arterial Hypertension. J Am Heart Assoc. 2021 Apr 6:e020548. doi: 10.1161/JAHA.120.020548. PMID: 33821682
Cooney SJ, Klawitter J, Khailova L, Robison J, Jaggers J, Ing RJ, Lawson S, Frank BS, Lujan SO, Davidson JA.
Regional lung metabolic profile in a piglet model of cardiopulmonary bypass with circulatory arrest.
Metabolomics. 2021 Sep 22;17(10):89. doi: 10.1007/s11306-021-01842-y. PMID: 34553313
Houska N, Ing RJ, Chatterjee D. Difficult Endotracheal Intubation in Adult Congenital Heart Disease Patients.
J Cardiothorac Vasc Anesth 2021 Aug 26:S1053-0770(21)00703-5. PMID: 34521581
Clopton R, Ing RJ, Kaufman J. Do Down Syndrome children require more opioids during cardiac surgery?" DOI: https://doi.org/10.1053/j.jvca.2021.09.039.
Stone ML, Albertz ML, Galambos C, Twite MD, Campbell DN, Di Maria M, Fonseca B, Miyamoto SD, Ing RJ. Multi-Disciplinary Management and Surgical Resection of Intracardiac Fibromas Causing Bilateral Ventricular Outflow Tract Obstructions in an Infant. Semin Cardiothorac Vasc Anesth. 2022 Aug 25;:10892532221123693. [Epub ahead of print] PubMed PMID: 36006828
Fernandez PG, Brockel MA, Lipscomb LL, Ing RJ, Tailounie M. Utilization of a Text and Translation Application for Communication with a Foreign Deaf Family: A Call for Validation of This Technology-A Case Report. A and A Case Rep. 2017 Apr 13. PMID: 28410257
McLennan D, Schäfer M, Barker AJ, Mitchell MB, Ing RJ, Browne LP, Ivy DD, Morgan GJ. Abnormal flow conduction through pulmonary arteries is associated with right ventricular volume and function in patients with repaired tetralogy of Fallot: does flow quality affect afterload?. Eur Radiol. 2022 Jul 19. [Epub ahead of print] PubMed PMID: 35852579
Iguidbashian KG, Robison J, Khailova L, Jaggers J, Ing R, Lawson S, Osorio Lujan SM, Klawitter J, Davidson JA. Changes in infant porcine pulmonary tissue oxylipins induced by cardiopulmonary bypass. Pediatr Res. 2022 Jun 9. [Epub ahead of print] PubMed PMID: 35681098
Houska N, Schafer M, Chatfield KC, Bernard TJ, Ing RJ. Anesthetic Considerations for Children With Multisystem Smooth Muscle Dysfunction Syndrome and Review of the Literature. J Cardiothorac Vasc Anesth. 2022 Aug;36(8 Pt B):3205-3211. PubMed PMID: 35568655
Clopton RG, Friesen RH, Partrick DA, Wilson N, Jaggers J, Ivy D, Schwartz LI, Ing RJ. The Anesthetic Challenges of Lung Biopsy–Associated Intrathoracic Hemorrhage in a Child with Suprasystemic Pulmonary Hypertension. Semin Cardiothorac Vasc Anesth 2017 Jun;21(2):172-177. PMID: 27815350
Zablah JE, Ing RJ. Which Pediatric Patients Require Postoperative Intensive Care After Cardiac Catheterization for Pulmonary Veins Stenosis?. J Cardiothorac Vasc Anesth. 2022 Aug;36(8 Pt A):2509-2510. PubMed PMID: 35545461
Ing RJ, Mayes L, Kramer R, Darst J, Twite M. Button Battery Ingestion in Children: a role for angiography? Canadian Journal of Anesthesia. Can J Anaesth. 2017 Mar; 64(3):321-322. PMID:27804024
Clopton R, Stone M, Ing RJ. In Children With Congenital Heart Disease Should the Left or Right Internal Jugular Vein Be Used for Central Venous Access?. J Cardiothorac Vasc Anesth. 2022 Aug;36(8 Pt A):2488-2489. PubMed PMID: 35537971
Ing RJ, Twite M, Barrett C. Review of the Society of Thoracic Surgeons Congenital Heart Surgery Database: 2017 Update on Outcomes and Quality implications for the Anesthesiologist. Journal of Cardiothoracic and Vascular Anesthesia. June 2017. doi.org/10.1053/j.jvca.2017.06.027
Davidson JA, Robison J, Khailova L, Frank BS, Jaggers J, Ing RJ, Lawson S, Iguidbashian J, Ali E, Treece A, Soranno DE, Osorio-Lujan S, Klawitter J. Metabolomic profiling demonstrates evidence for kidney and urine metabolic dysregulation in a piglet model of cardiac surgery-induced acute kidney injury. Am J Physiol Renal Physiol. 2022 Jul 1;323(1):F20-F32. PubMed PMID: 35532069
Kim JS, Ellis WC, Ing RJ. Does the Volume and Constitution of Cardiopulmonary Bypass Priming Fluids Affect Blood Loss After Cardiac Surgery in Children?. J Cardiothorac Vasc Anesth. 2022 Jun;36(6):1595-1597. PubMed PMID: 35148942
Ing RJ, Hoagland M, Mayes L, Twite M. The anesthetic management of button battery ingestion. Accepted to Canadian Journal of Anesthesia October 2017.
Clopton RC, Ing RJ, Kaufman J. Do Children With Down Syndrome Require More Opioids During Cardiac Surgery?. J Cardiothorac Vasc Anesth. 2022 Jan;36(1):200-201. PubMed PMID: 34674930
Twite M, Ing RJ, Nichols C, Yaster M. Outstanding contribution to pediatric anesthesiology: an interview with Dr. Robert H. Friesen Paediatr Anaesth. 2017 Oct;27(10):991-996. doi: 10.1111/pan.13215. Epub 2017 Sep 5. PMID: 28872749
1. Waldman JC, Whitney GM, Twite MD, Ing RJ. Institutional specific risk stratification of children with congenital heart disease undergoing non-cardiac procedures. What are the risks of anesthesia at your institution? J Cardiothorac Vasc Anesth. 2023 May 5:S1053-0770(23)00276-8. doi: 10.1053/j.jvca.2023.04.041. PMID: 3722554.
1. McLennan D, Schäfer M, Barker AJ, Mitchell MB, Ing RJ, Browne LP, Ivy DD, Morgan GJ. Abnormal flow conduction through pulmonary arteries is associated with right ventricular volume and function in patients with repaired tetralogy of Fallot: does flow quality affect afterload? Eur Radiol. 2023 Jan;33(1):302-311. doi: 10.1007/s00330-022-09017-6. Epub 2022 Jul 19. PMID: 35852579
68. Ing RJ, Orfila JE, Basak JM, Joksimovic S, Schroeder C, Lujan SO, Quillinan N, Todorovic SM, Herson PS, Davidson J35700 Acute hippocampal dysfunction following deep hypothermic cardiac arrest in a juvenile piglet model AUA Poster Session B Hyatt Regency poster 44 Denver AUA meeting 4/13/2023, 3:30 pm - 4:30 pm
69. Thomson L, Davidson J, Frank B, Stone M, Ali E, Ing RJ, Syed A, Khailova L, Neonatal and Cardiac Intensive Care/ECMO”. World Congress of Pediatric Cardiology and Cardiac Surgery Annual Meeting 2023
Ing RJ, Twite M. The Year in Review. Semin Cardiothorac Vasc Anesth. 2017 Mar;21(1):17-22. PMID: 28107799
Ing RJ. Anesthetic outcomes in Tetralogy of Fallot with absent pulmonary valve. Journal of Cardiothoracic and Vascular Anesthesia April 2017. PMID: 28465119.
Twite M, Ing RJ, Schwartz L. Springer Book: 86874081_da Cruz. Intensive Care of the Adult with Congenital Heart Disease¬ Series: Congenital Heart Disease in Adolescents and Adults. June 2017
70. Iguidbashian J, Mancuso C, Khailova L, Suarez Pierre A, , Lehmann T, Osorio Lujan S, Ali E, Lee S M Ing RJ, Stone M, Frank B, Davidson J. Gene expression differs by organ following cardiopulmonary bypass with circulatory arrest in a transcriptome profile analysis. 8th World Congress of Pediatric Cardiology and Cardiac Surgery Washington DC August 27- September 1 2023.